Edelfosine Induced Suicidal Death of Human Erythrocytes

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Edelfosine Induced Suicidal Death of Human Erythrocytes.

BACKGROUND/AIMS The anti-inflammatory, anti-autoimmune, antiparasitic, and anti-viral ether phospholipid edelfosine (1-O-octadecyl-2-O-methylglycero-3-phosphocholine) stimulates apoptosis of tumor cells and is thus considered for the treatment of malignancy. Similar to apoptosis of nucleated cells, erythrocytes may enter eryptosis, the suicidal erythrocyte death characterized by cell shrinkage ...

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ژورنال

عنوان ژورنال: Cellular Physiology and Biochemistry

سال: 2015

ISSN: 1015-8987,1421-9778

DOI: 10.1159/000438578